Journal Publications

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

Lu-Chen Weng, Amelia Weber Hall, Seung Hoan Choi, Sean J. Jurgens, Jeffrey Haessler, Nathan A. Bihlmeyer, Niels Grarup, Honghuang Lin, Alexander Teumer, Ruifang Li-Gao, Jie Yao, Xiuqing Guo, Jennifer A. Brody, Martina Müller-Nurasyid, Katharina Schramm, Niek Verweij, Marten E. van den Berg, Jessica van Setten, Aaron Isaacs, Julia Ramírez, (…), Patrick T. Ellinor, and Steven A. Lubitz

Circulation: Genomic and Precision Medicine

Genetic Basis and Prognostic Value of Exercise QT Dynamics

Stefan van Duijvenboden, Julia Ramírez, William J. Young, Borbala Mifsud, Michele Orini, Andrew Tinker, Patricia B. Munroe, Pier D. Lambiase

Circulation: Genomic and Precision Medicine

Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval

Julia Ramírez, Stefan van Duijvenboden, William J. Young, Michele Orini, Pier D. Lambiase, Patricia B. Munroe, Andrew Tinker

American Journal of Human Genetics

The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank

Judit García-González, Julia Ramírez, David M Howard, Caroline H Brennan, Patricia B MunroeRobert Keers

Translational Psychiatry 10(1), 1-‌10, Nature Publishing Group, 2020/‌9/‌28

Conference Publications

Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate (pdf)

Stefan van Duijvenboden, Julia Ramírez, William J Young, Andrew Tinker, Patricia BMunroe, Pier D Lambiase, Michele Orini.

2020 Computing in Cardiology (CiNC).

Will genetic data significantly change cardiovascular risk prediction in daily practice? (pdf)

William J Young, Julia Ramírez, Stefan van Duijvenboden, Andrew Tinker, Pier DLambiase, Patricia B Munroe, Michele Orini.

2020 Computing in Cardiology (CiNC).

Potassium Monitoring from Multilead T-wave Morphology Changes duringHemodyalisis: Periodic versus Principal Component Analysis. (pdf)

Flavio Palmieri1, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martín-Yebra, Esther Pueyo, Pablo Laguna, Juan Pablo Martínez, Julia Ramírez.

2020 Computing in Cardiology (CiNC).

Sex Differences in the Morphology of RR-Matched T-waves (pdf)

Julia Ramírez, Stefan van Duijvenboden, Andrew Tinker, Pier D Lambiase, Patricia B Munroe, Michele Orini.

2020 Computing in Cardiology (CiNC).

Interaction between ECG and Genetic Markers of Coronary Artery Disease. (pdf)

Julia Ramírez, Stefan van Duijvenboden, William J. Young, Andrew Tinker, Pier D Lambiase,Patricia B Munroe, Michele Orini.

2020 Computing in Cardiology (CiNC).

Journal Publications

Resting Heart Rate and Type 2 Diabetes: A Complex Relationship in Need of Greater Understanding

Patricia B. MunroeJulia Ramírez and Stefan van Duijvenboden

Journal of the American College of Cardiology, Volume 74, Issue 17, October 2019.

Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics

Julia Ramírez, Stefan van Duijvenboden, Nay Aung, Pablo Laguna, Esther Pueyo, Andrew Tinker, Pier D. Lambiase, Michele Orini, Patricia B. Munroe

Circulation: Arrhythmia and Electrophysiology. 2019;12:e007549

Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants.

Fung, Kenneth; Ramírez, Julia; Warren, Helen R; Aung, Nay; Lee, Aaron M; Tzanis, Evan; Petersen, Steffen E; Munroe, Patricia B.

Scientific Reports, 9, Article number: 9143 (2019)

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction.

Ioanna Ntalla, Lu-Chen Weng, James H Cartwright, (…), Julia Ramirez, Stefan Van Duijvenboden, David O. Arnar, Daniel F. Gudbjartsson, Hilma Holm, Patrick Sulem, Gudmar Thorleifsson, Rosa Thorolfsdottir, Unnur Thorsteinsdottir, Emelia Benjamin, Andrew Tinker, Kari Stefansson, Patrick T. Ellinor, Yalda Jamshidi, Steven A. Lubitz, Patricia B. Munroe

bioRxiv

Conference Publications

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels

Hassaan A Bukhari, Flavio Palmieri, Dina Ferreira, Mark Potse, Julia Ramírez, Pablo Laguna, Carlos Sánchez, Esther Pueyo.

2019 Computing in Cardiology (CiNC).

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients

Flavio Palmieri, Pedro Gomis, Dina Ferreira, José Esteban Ruiz, Beatriz Bergasa, Alba Martín-Yebra, Hassaan A. Bukhari, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez, Pablo Laguna.

2019 Computing in Cardiology (CiNC).

The Genetic Architecture of T-wave Morphology Restitution.

Ramírez, Julia, van Duijvenboden, S., Laguna, P., Pueyo, E., Tinker, A., Lambiase, P., Orini, M., Munroe, P.,

CompBioMed Conference, London, United Kingdom.

21 The cardiovascular predictive value and genetic basis of T-wave morphology.

Ramirez, Julia; van Duijvenboden, Stefan; Tinker, Andrew; Lambiase, Pier; Orini, Michele; Munroe, Patricia B.

British Cardiovascular Society, Manchester, United Kingdom.

22 Cardiac repolarization during exercise reveals independent prognostic information for cardiovascular risk prediction.

van Duijvenboden, Stefan; Ramirez, Julia; Orini, Michele; Tinker, Andrew; Munroe, Patricia B; Lambiase, Pier.

British Cardiovascular Society, Manchester, United Kingdom.

Journal Publications

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.

Bram P Prins, Timothy J Mead, Jennifer A Brody, Gardar Sveinbjornsson, Ioanna Ntalla, Nathan A Bihlmeyer, Marten van den Berg, Jette Bork-Jensen, Stefania Cappellani, Stefan Van Duijvenboden, Nikolai T Klena, George C Gabriel, Xiaoqin Liu, Cagri Gulec, Niels Grarup, Jeffrey Haessler, Leanne M Hall, Annamaria Iorio, Aaron Isaacs, Ruifang Li-Gao, Honghuang Lin, Ching-Ti Liu, Leo-Pekka Lyytikäinen, Jonathan Marten, Hao Mei, Martina Müller-Nurasyid, Michele Orini, Sandosh Padmanabhan, Farid Radmanesh, Julia Ramirez, (…), Patricia B Munroe, Dan E Arking, Cecilia W Lo, Yalda Jamshidi.

Genome biology, 19, Article number: 87 (2018)

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.

Ramírez, Julia; van Duijvenboden, Stefan; Ntalla, Ioanna; Mifsud, Borbala; Warren, Helen R; Tzanis, Evan; Orini, Michele; Tinker, Andrew; Lambiase, Pier D; Munroe, Patricia B.

Nature Communications, 9, Article number: 1947 (2018)

Conference Publications

23 T-wave morphology restitution predicts arrhythmic risk in the UK biobank cohort.

Ramírez, J; van Duijvenboden, S; Orini, M; Tinker, A; Munroe, PB; Lambiase, PD.

Heart Rhythm Conference, Birmingham, United Kingdom.

2 QT interval and exercise qt dynamics from 58,852 individuals in UK biobank predict ventricular arrhythmias and heart failure.

van Duijvenboden, S; Ramírez, J; Orini, M; Tinker, A; Munroe, PB; Lambiase, PD.

Heart Rhythm Conference, Birmingham, United Kingdom.

T-Wave Morphology Restitution in Chronic Heart Failure Patient With Atrial Fibrillation.

Palmieri, Flavio; Burattini, Laura; Martínez, Juan Pablo; Ramírez, Julia.

Computing in Cardiology Conference (CinC), Maastrich, The Netherlands.

Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology.

Ramírez, Julia; Van Duijvenboden, Stefan; Laguna, Pablo; Pueyo, Esther; Tinker, Andrew; Lambiase, Pier D; Munroe, Patricia B; Orini, Michele.

Computing in Cardiology Conference (CinC), Maastrich, The Netherlands.

Journal Publications

Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model.

Ramírez, Julia; Orini, Michele; Mincholé, Ana; Monasterio, Violeta; Cygankiewicz, Iwona; de Luna, Antonio Bayés; Martínez, Juan Pablo; Laguna, Pablo; Pueyo, Esther.

PLoS One, 12(10): e0186152.

Variability of ventricular repolarization dispersion quantified by time-warping the morphology of the T-waves.

Ramírez, Julia; Orini, Michele; Tucker, J Derek; Pueyo, Esther; Laguna, Pablo.

IEEE Transactions on Biomedical Engineering, Volume: 64 , Issue: 7 , July 2017.

T‐Wave Morphology Restitution Predicts Sudden Cardiac Death in Patients With Chronic Heart Failure.

Ramírez, Julia; Orini, Michele; Mincholé, Ana; Monasterio, Violeta; Cygankiewicz, Iwona; Bayés de Luna, Antonio; Martínez, Juan Pablo; Pueyo, Esther; Laguna, Pablo.

Journal of the American Heart Association, 2017;6:e005310.

Conference Publications

T-wave morphology restitution dependency with heart rate range and its association with sudden cardiac death in chronic heart failure.

Ramírez, Julia; Orini, Michele; Pueyo, Esther; Laguna, Pablo.

Computing in Cardiology (CinC), Rennes, France.

Quantification of T-wave Morphological Variability Using Time-warping Methods.

Ramírez, Julia; Orini, Michele; Pueyo, Esther; Laguna, Pablo.

EMBEC & NBC 2017, Tampere, Finland.

Conference Publications

Postextrasystolic T wave change to stratify risk of pump failure death in patients with chronic heart failure.

Lenis, Gustavo; Menges, Robert; Ramírez, Julia; Cygankiewicz, Iwona; de Luna, Antoni Bayés; Martínez, Juan Pablo; Laguna, Pablo; Dössel, Olaf.

Computing in Cardiology Conference (CinC), Vancouver, Canada.

An index for T-wave pointwise amplitude variability quantification.

Ramírez, Julia; Orini, Michele; Tucker, J Derek; Pueyo, Esther; Laguna, Pablo.

Computing in Cardiology Conference (CinC), Vancouver, Canada.

Journal Publications

Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers.

Ramírez, Julia; Monasterio, Violeta; Mincholé, Ana; Llamedo, Mariano; Lenis, Gustavo; Cygankiewicz, Iwona; de Luna, Antonio Bayés; Malik, Marek; Martínez, Juan Pablo; Laguna, Pablo.

Journal of electrocardiology, Volume 48, Issue 4, July–August 2015, Pages 551-557.

Journal Publications

QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death.

Ramírez, Julia; Laguna, Pablo; de Luna, Antonio Bayés; Malik, Marek; Pueyo, Esther.

Journal of electrocardiology, Volume 47, Issue 6, November–December 2014, Pages 842-848.

Conference Publications

Circadian pattern and sex differences of QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure patients.

Ramírez, Julia; Cygankiewicz, Iwona; Laguna, Pablo; Malik, Marek; Pueyo, Esther.

Computing in Cardiology Conference (CinC), Boston, USA.

Conference Publications

Sudden Cardiac Death Survival Prediction from Restitution Dispersion Analysis.

Ramírez, Julia; Mincholé, Ana; Bolea, Juan; Laguna, Pablo; Pueyo, Esther.

JORNADA DE JÓVENES INVESTIGADORES DEL I3A

Prediction of sudden cardiac death in chronic heart failure patients by analysis of restitution dispersion

J Ramírez, A Mincholé, J Bolea, P Laguna, E Pueyo

Computing in Cardiology Conference (CinC), Zaragoza, Spain.