Publications

Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size

Munroe, P.B., Aung, N. & Ramírez, J

Nat Genet (2024)

Ventricular restitution predicts paroxysmal atrial fibrillation in horses

J. Ramírez and A. Tinker

Function 2020; 2(1): zqaa038.

Contribution: compiling information, drafting and editing the manuscript and Figure.

Resting heart rate and type 2 diabetes – a complex relationship in need of greater understanding

P. B. Munroe, J. Ramírez and S. van Duijvenboden

Journal of the American College of Cardiology 2019; 74(17)

Contribution: compiling information, drafting and editing the manuscript.

Deep learning to predict left ventricular hypertrophy from the electrocardiogram

Hafiz Naderi, Thomas Kaplan, Stefan van Duijvenboden, Esmeralda Ruiz Pujadas, Nay Aung, C Anwar A Chahal, Karim Lekadir, Bishwas Chamling, Marcus Dörr, Marcello R P Markus, Steffen E Petersen, Julia Ramírez, Patricia B Munroe

Europace. 2026 Feb 3;28(2):euag015

DOI: 10.1093/europace/euag015

Cardiac magnetic resonance characteristics and prognostic associations of hypertension-mediated left ventricular hypertrophy

Hafiz Naderi , Stefan van Duijvenboden , Julia Ramírez , Sucharita Chadalavada , Elisa Rauseo , Nay Aung , Steffen E Petersen , Patricia B Munroe

European Heart Journal – Imaging Methods and Practice, Volume 4, Issue 1, January 2026

DOI: 10.1093/ehjimp/qyaf168

Gianfranco Parati , Juan Eugenio Ochoa, (…), Julia Ramírez, (…), Alberto Avolio , Paolo Castiglioni

European Journal of Preventive Cardiology, Volume 33, Issue 7, May 2026, Pages 1058–1071

DOI: 10.1093/eurjpc/zwag058

Sudden Cardiac Death Risk Prediction From QT–RR Adaptation Time Lag Computed From Exercise Stress Test ECG

Cristina Pérez; Juan Pablo Martínez; Julia Ramírez; Tuomas Kenttä; Juhani Junttila; Antti Kiviniemi

IEEE Transactions on Biomedical Engineering, vol. 73, no. 4, pp. 1493-1503, April 2026

DOI: 10.1109/TBME.2025.3607144

T-wave Peak-to-End Changes, Quantified by Time-Warping, Surrogates Ventricular Repolarization Dispersion for Ventricular Fibrillation Prediction in a Porcine Myocardial Infarction Model

Neurys Gómez; Alena S. Abramochkina; Julia Ramírez; Alexey O. Ovechkin; Olesya G. Bernikova; Pyotr G. Platonov

IEEE Transactions on Biomedical Engineering. 2026.

DOI: 10.1109/TBME.2026.3683284

Clinical value of ECG-derived markers for risk stratification in sudden cardiac arrest due to Chagas cardiomyopathy

Ángela Hernández, João Paulo Madeiro, Roberto C. Pedrosa, Pablo Laguna, Julia Ramírez

Revista española de Cardiología, 2026.

DOI: 10.1016/j.rec.2026.05.005

Neurys Gómez, Julia Ramírez, Aleksei A. Savelev, Pia Dahlberg, MD, Anneli Svensson, Nina Larsson, Erik Ljungström, Uzma Chaudhry, Juan Pablo Martínez, Pablo Laguna, and Pyotr G. Platonov

Journal of the American Heart Association. Volume 15, Number 13

DOI: 10.1161/JAHA.125.048388

Imaging-Derived Sarcopenic Obesity and Cardiovascular Outcomes: Insights Into Heart Failure Risk and Muscle Biology

Mihir M. Sanghvi m.sanghvi@qmul.ac.uk, Hannah L. Nicholls, Thomas M. Kaplan, Sucharitha Chadalavada, Julia Ramírez, Tanner Stokes, Changhyun Lim, Jonathan C. Mcleod, Stuart M. Phillips, Bethan E. Phillips, Philip J. Atherton, Mohammed Y. Khanji, Steffen E. Petersen, James A. Timmons, Patricia B. Munroe, and Nay Aung

JACC Volume 88, Number 6

Unsupervised clustering of single-lead electrocardiograms associates with prevalent and incident heart failure in coronary artery disease

Josseline Madrid , William J Young , Stefan van Duijvenboden , Michele Orini , Patricia B Munroe , Julia Ramírez , Ana Mincholé

European Heart Journal – Digital Health, Volume 6, Issue 3, May 2025, Pages 435–446

DOI: 10.1093/ehjdh/ztaf013

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Roelof A. J. Smit, Kaitlin H. Wade, (…), Julia Ramírez, (…), Sonja I. Berndt & Ruth J. F. Loos

Nature Medicine volume 31, pages: 3151–3168 (2025)

Using Genomics to Develop Personalized Cardiovascular Treatments

Mihir M. Sanghvi, William J. Young, Hafiz Naderi, Richard Burns, Julia Ramírez, Christopher G. Bell, and Patricia B. Munroe

Arteriosclerosis, Thrombosis, and Vascular Biology. Volume 45, Number 6

DOI: 10.1161/ATVBAHA.125.319221

Diagnostic and prognostic value of ECG-predicted hypertension-mediated left ventricular hypertrophy using machine learning

Hafiz Naderi, Julia Ramírez, Stefan Van Duijvenboden, Esmeralda Ruiz Pujadas, Nay Aung, Lin Wang, Bishwas Chamling, Marcus Dörr, Marcello R.P. Markus, Choudhary Anwar A. Chahal, Karim Lekadir, Steffen E. Petersen, Patricia B. Munroe

Journal of Hypertension 43(8):p 1327-1338, August 2025.

DOI: 10.1097/HJH.0000000000004034

Heart Rate Profiles During Exercise and Incident Parkinson’s Disease

Stefan van Duijvenboden PhD, Julia Ramírez PhD, Job Scheurink BSc, Sirwan K. L. Darweesh PhD, Michele Orini PhD, Andrew Tinker PhD, Patricia B. Munroe PhD, Jos Thannhauser PhD, Luc Evers MSc, Joanna IntHout PhD, Pier D. Lambiase PhD, Bastiaan R. Bloem PhD, Aiden Doherty PhD, Marc A. Brouwer PhD

Annals of Neurology. Volume98, Issue5. November 2025. Pages 1004-1013

DOI: https://doi.org/10.1002/ana.70010

Relationships of Circulating Plasma Metabolites With the QT Interval in a Large Population Cohort

William J. Young, PhD, Mihir M. Sanghvi, Julia Ramírez, Michele Orini, Stefan van Duijvenboden, PhD, Helen R. Warren, Andrew Tinker, Pier D. Lambiase, and Patricia B. Munroe

Circulation: Genomic and Precision Medicine. Volume 18, Number 5

DOI: https://doi.org/10.1161/CIRCGEN.124.004978

Phenotypic expression of rare progressive cardiac conduction disease variants in the general population

Ravi A Shah, Julia Ramírez, Claire Kirkby, Charlotte Ives, Martin Lowe, Patricia B Munroe, Pier D Lambiase, William J Young

Europace. 2025 Jun 3;27(6):euaf103

DOI: 10.1093/europace/euaf103.

Relationships between heart shape, function, and disease in 38,858 UK biobank participants

Richard Burns, Laura Dal Toso, Charlène A. Mauger, Alireza Sojoudi, Avan Suinesiaputra, Steffen E. Petersen, Julia Ramírez, Patricia B. Munroe, Alistair A. Young

Journal of Cardiovascular Magnetic Resonance. Winter 2025

State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology

Emma Svennberg, Janet K Han ,(…) , Julia Ramírez, Jagmeet P Singh, (…), Alessandro Zorzi

EP Europace, Volume 27, Issue 5, May 2025, euaf071,

DOI: https://doi.org/10.1093/europace/euaf071

RoePINNs: An integration of advanced CFD solvers with Physics-Informed Neural Networks and application in arterial flow modeling

J. Orera, J. Ramírez, P. García-Navarro, J. Murillo

Computer Methods in Applied Mechanics and Engineering. 15 May 2025

Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size

Patricia B. Munroe, Nay Aung & Julia Ramírez

Nature Genetics volume 56, pages197–199 (2024)

Fine mapping of candidate effector genes for heart rate

Julia Ramírez, Stefan van Duijvenboden, William J Young, Yutang Chen, Tania Usman, Michele Orini, Pier D Lambiase, Andrew Tinker, Christopher G Bell, Andrew P Morris, Patricia B Munroe

Hum Genet. 2024 Oct;143(9-10):1207-1221.

DOI: 10.1007/s00439-024-02684-z

Genome‐Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants

William J. Young, Peter J. van der Most, Traci M. Bartz, (…), Julia Ramírez, (…), and Patricia B. Munroe

Journal of the American Heart Association, Volume 13, Number 17

DOI: https://doi.org/10.1161/JAHA.123.034760

Mihir M. Sanghvi, Julia Ramírez, Sucharitha Chadalavada, Nay Aung, Patricia B. Munroe, Nikolaos Donos, and Steffen E. Petersen

JACC: Advances Volume 3, Number 10

T-Wave Peak-to-End Changes Quantified by Time-Warping Predicts Ventricular Fibrillation in a Porcine Myocardial Infarction Model

Neurys Gómez; Julia Ramírez; Alba Martín-Yebra; Marina M. Demidova; Pyotr Platonov; Juan Pablo Martínez

IEEE Transactions on Biomedical Engineering ( Volume: 71, Issue: 10, October 2024)

DOI: 10.1109/TBME.2024.3404254

Stefan van Duijvenboden, Christopher P Nelson, Zahra Raisi-Estabragh, Julia Ramirez, Michele Orini, Qingning Wang, Nay Aung, Veryan Codd, Svetlana Stoma, Elias Allara, Angela M Wood, Emanuele Di Angelantonio, John Danesh, Nicholas C Harvey, Steffen E Petersen, Patricia B Munroe, Nilesh J Samani

Heart. 2025 Mar 13;111(7):314-320.

doi: 10.1136/heartjnl-2024-324875

Genetic basis of right and left ventricular heart shape

Richard Burns, William J. Young, Nay Aung, Luis R. Lopes, Perry M. Elliott, Petros Syrris, Roberto Barriales-Villa, Catrin Sohrabi, Steffen E. Petersen, Julia Ramírez, Alistair Young & Patricia B. Munroe

Nature Communications volume 15, Article number: 9437 (2024)

Leucocyte telomere length and conduction system ageing

Stefan van Duijvenboden, Christopher P Nelson, Zahra Raisi-Estabragh, Julia Ramirez, Michele Orini, Qingning Wang, Nay Aung, Veryan Codd, Svetlana Stoma, Elias Allara, Angela M Wood, Emanuele Di Angelantonio, John Danesh, Nicholas C Harvey, Steffen E Petersen, Patricia B Munroe, Nilesh J Samani

Heart Published Online First: 17 December 2024 (2024).

S. van Duijvenboden, J. Ramírez, M. Orini, N. Aung, S. Petersen, A. Doherty, A. Tinker, P. Munroe, P. Lambiase

Circulation 2023; 148:1932-1944

Long-term association of ultra-short heart rate variability with cardiovascular events

Michele Orini, Stefan van Duijvenboden, William J. Young, Julia Ramírez, Aled R. Jones, Alun D. Hughes, Andrew Tinker, Patricia B. Munroe & Pier D. Lambiase

Scientific reports 2023; 13, 18966.

Time-Warping Analysis of the T-Wave Peak-to-End Interval to Quantify Ventricular Repolarization Dispersion During IschemiaPredicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using machine learning

Neurys Gómez; Julia Ramírez; Juan Pablo Martínez; Pablo Laguna

IEEE Journal of Biomedical and Health Informatics 2023; 27(11):5314-5325

Integration of genetic-fine mapping and multi-omics data reveals candidate effector genes for hypertension

S. van Duijvenboden, J. Ramírez, W. J. Young, K. J. Olczak, F. Ahmed, M. J. A. Y. Alhammadi, ICBP, C. G. Bell, A. P. Morris and P. B. Munroe.

American Journal of Human Genetics 2023; 110(10):1718-1734

Predicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using machine learning

Hafiz Naderi, Julia Ramírez, Stefan van Duijvenboden, Esmeralda Ruiz Pujadas, Nay Aung, Lin Wang, C Anwar A Chahal, Karim Lekadir, Steffen E Petersen, Patricia B Munroe

European Heart Journal – Digital Health 4(4):316-324

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

William J. Young, Jeffrey Haessler, Jan-Walter Benjamins, (…), Julia Ramírez, (…), Pier D. Lambiase, Larisa G. Tereshchenko & Patricia B. Munroe

Nature Communications volume 14, Article number: 1411 (2023)

Premature atrial and ventricular contractions detected on wearable-format ECGs and prediction of cardiovascular events

Michele Orini, Stefan van Duijvenboden, William J Young, Julia Ramírez, Aled R Jones, Andrew Tinker, Patricia B Munroe, Pier D Lambiase

European Heart Journal – Digital Health, ztad007

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, …, Julia Ramírez, …, Hampton L Leonard

Genome biology 23(1), 1-‌42, BioMed Central, 2022/‌12

A saturated map of common genetic variants associated with human height

Loïc Yengo, Sailaja Vedantam, Eirini Marouli, Julia Sidorenko, …, Julia Ramírez, …, Peter M. Visscher & Joel N. Hirschhorn

JOURNAL OF HUMAN HYPERTENSION 36 (SUPPL 1), 4-‌4, 2022

Classifying hypertension mediated left ventricular hypertrophy patterns from the electrocardiogram using machine learning

Hafiz Naderi, Julia Ramírez, Stefan van Duijvenboden, Esmeralda Ruiz Pujadas, Lin Wang, Karim Lekadir, Steffen Petersen, Patricia Munroe

JOURNAL OF HUMAN HYPERTENSION 36 (SUPPL 1), 4-‌4, 2022

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

William J. Young, Najim Lahrouchi, Aaron Isaacs, ThuyVy Duong,…, Julia Ramirez, …, Christopher Newton-Cheh & Patricia B. Munroe

Nature Communications volume 13, Article number: 5144 (2022)

ECG T‐Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low‐ and Moderate‐Risk Populations

Julia Ramírez, Antti Kiviniemi, Stefan van Duijvenboden, Andrew Tinker, Pier D. Lambiase, Juhani Junttila, Juha S. Perkiömäki, Heikki V. Huikuri, Michele Orini and Patricia B. Munroe

Journal of the American Heart Association. 2022;11:e025897

ECG T-wave Morphology Variations Predict Ventricular Arrhythmic Risk in Low- and Moderate-risk Populations

J. Ramírez, A. Kiviniemi, S. van Duijvenboden, A. Tinker, P. D. Lambiase, J. Junttila, J. S. Perkiömäki, H. V. Huikuri, M. Orini, P. B. Munroe

Journal of the American Heart Association (In Press)

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

S. Ramdas, J. Judd, S. E. Graham, (…), J. Ramírez, (…), C. J. Willer, X. Zhu, C. D. Brown

American Journal of Human Genetics (In Press)

Prediction of coronary artery disease and major adverse cardiovascular events using clinical and genetic risk scores for cardiovascular risk factors

J. Ramírez, S. van Duijvenboden, W.J. Young, A. Tinker, P.D. Lambiase, M. Orini, P.B. Munroe

Circulation – Genomics and Precision Medicine (In Press)

Weighted Time Warping Improves T-wave Morphology Markers Clinical Significance

F. Palmieri, P. Gomis, D. Ferreira, E. Pueyo, J. P. Martínez, P. Laguna and J. Ramírez

IEEE Transactions on Biomedical Engineering (In Press), doi: 10.1109/TBME.2022.3153791.

The power of genetically diverse individuals in genome-wide association studies of blood lipid levels

S.E. Graham, S.L. Clarke, K.H.Wu, (…), J. Ramírez, (…), P. Deloukas, Y.V. Sun and C.J. Willer

Nature 600, 675-679

Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders

S. van Duijvenboden*, J. Ramírez*, W. Young, M. Orini, B. Mifsud, A. Tinker, P. Lambiase, P. B. Munroe

Human Molecular Genetics, ddab197

Analysing electrocardiographic traits and predicting cardiac risk in UK Biobank

J. Ramírez, S. van Duijvenboden, W.J. Young, M. Orini, A. Jones, P. Lambiase, P. Munroe, A. Tinker

JRSM Cardiovascular Disease, January 2021

ECG-based Monitoring of Blood Potassium Concentration: Periodic versus Principal Component as Lead Transformation for Biomarker Robustness

F. Palmieri, P. Gomis, D. Ferreira, A. Martín-Yebra, Esther Pueyo, J. P. Martínez, J. Ramírez, P. Laguna

Biomedical Signal Processing and Control 2021, 68: 102719

A novel two-stage heart arrhythmia ensemble classifier

M.J. Rezaei, J.R. Woodward, J. Ramírez, P.B. Munroe

Computers 2021, 10(5), 60

Genetically-Determined Serum Calcium levels and Markers of Ventricular Repolarisation: A Mendelian Randomization Study in the UK Biobank

WJ Young, HR Warren, DO Mook-Kanamori, J Ramírez, S van Duijvenboden, M Orini, A Tinker, D van Heemst, PD Lambiase, JW Jukema, PB Munroe, R Noordam

Circulation Genomics and Precision Medicine 2021; 14(3):e003231

Nonlinear T-wave Time Warping-based Sensing Model for Non-invasive Personalized Blood Potassium Monitoring in Hemodialysis Patients

F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, A. Martín-Yebra, E. Pueyo, J.P. Martínez, J. Ramírez, P. Laguna

Sensors 2021, 21(8), 2710.

Monitoring Blood Potassium Concentration in Hemodialysis Patients by Quantifying T-wave Morphology Dynamics

F. Palmieri, P. Gomis, J. Ruiz, B. Bergasa, D. Ferreira, A. Martín-Yebra, H. Ahmed, J. P. Martínez, E. Pueyo, J. Ramírez, P. Laguna

Scientific Reports 11, 3883.

No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: a Mendelian Randomization Analysis

J. Mensah-Kane, A. F. Schmidt, A. D. Hingorani, C. Finan, Y. Chen, S. van Duijvenboden, M. Orini, P. D. Lambiase, A. Tinker, E. Marouli, P. B. Munroe* and J. Ramírez*

Frontiers in Genetics 12(59)

Characterization of T wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate

H. Ahmed, F. Palmieri, J. Ramírez, P. Laguna, J. Ruiz, D. Ferreira, M. Potse, C. Sanchez-Tapia, E. Pueyo

IEEE Transactions on Biomedical Engineering 68(8), 2467-2478

A method to minimise the impact of ECG marker inaccuracies on the spatial QRS-T angle: Evaluation on 1,512 manually annotated ECGs

W. J. Young, S. van Duijvenboden, J. Ramírez, A. Jones, A. Tinker, P. B. Munroe, P. D. Lambiase, M. Orini

Biomedical Signal Processing and Control 64, 102305

The effects of polygenic risk for psychiatric disorders and smoking behavior on psychotic experiences in UK Biobank

J. García-González, J. Ramírez, D. M. Howard, C. H. Brennan, P. B. Munroe, R. Keers

Translational Psychiatry 2020; 10(330)

Contribution: Supervision and editing the manuscript.

Genetic determinants of electrocardiographic P-wave duration and relation to atrial fibrillation

L. C. Weng, A. Hall, S. H. Choi, (…), J. Ramírez, (…), K. Lunetta, P. Ellinor, and S. Lubitz.

Circulation: Genomic and Precision Medicine 2020; 13:387-395

Contribution: Individual study analyst and data contributor for the meta-analysis.

Genetic Basis and Prognostic Value of Exercise QT Dynamics

S. van Duijvenboden*, J. Ramírez*, W. J. Young, B. Mifsud, M. Orini, A. Tinker, P. B. Munroe and P. D. Lambiase

Circulation: Genomic and Precision Medicine 2020; 13(4)

Contribution: Second leading author, data analysis, manuscript drafting and editing.

Common Genetic Variants Modulate the Electrocardiographic T-peak-to-end Interval

J. Ramírez*, S. van Duijvenboden*, W. J. Young, M. Orini, P. Lambiase, P. B. Munroe, A. Tinker

American Journal of Human Genetics 2020; 106(6):764-778

Contribution: First leading author, data analysis, manuscript drafting and editing.

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

Ntalla, L. C. Weng, J. Cartwright, (…), J. Ramírez, (…), Y. Jamshidi , S. Lubitz and P. B. Munroe

Nature Communications 2020; 11(1):1-12

Contribution: Individual study analyst and data contributor for the meta-analysis.

Cardiovascular predictive value and genetic basis of ventricular repolarization dynamics

J. Ramírez, S. van Duijvenboden, N. Aung, P. Laguna, E. Pueyo, A. Tinker, P. D. Lambiase, M. Orini and P.B. Munroe

Circulation: Arrhythmia and Electrophysiology 2019; 12:e007549

Contribution: Leading author, data analysis, manuscript drafting and editing.

Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants

K. Fung, J. Ramírez, H. R. Warren, N. Aung, A. M. Lee, E. Tzanis, S. E. Petersen and P. B. Munroe

Scientific Reports 2019; 9:9143

Contribution: Supervision and editing the manuscript.

The effects of polygenic risk for psychiatric disorders and smoking behavior on psychotic experiences in UK Biobank

J. García-González, J. Ramírez, D. M. Howard, C. H. Brennan, P. B. Munroe, R. Keers

Translational Psychiatry 2020; 10(330)

Contribution: Supervision and editing the manuscript.

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

B. P. Prins, T. J. Mead, J. A. Brody, (…), J. Ramirez, (…), P. B Munroe, D. E Arking, C. W Lo, Y. Jamshidi

Genome Biology 2018; 19(1):87

Contribution: Individual study analyst and data contributor for the meta-analysis.

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

J. Ramírez*, S. van Duijvenboden*, I. Ntalla*, B. Mifsud, H. R. Warren, E. Tzanis, M. Orini, A. Tinker, P. D. Lambiase and P. B. Munroe

Nature Communications 2018; 9(1):1947

Contribution: First leading author, data analysis, manuscript drafting and editing.

Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model

J. Ramírez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz, A. Bayes de Luna, J. P. Martinez, P Laguna and E. Pueyo

PLoS ONE 2017; 12(10):e0186152.

Contribution: Leading author, data analysis, manuscript drafting and editing.

T-wave Morphology Restitution Predicts Sudden Cardiac Death in Patients with Chronic Heart Failure

J. Ramírez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz, A. Bayes de Luna, J. P. Martinez, E. Pueyo and P. Laguna

JAHA 2017; 6(5):e005310.

Variability of ventricular repolarization dispersion quantified by time-warping the morphology of the T-waves

J. Ramírez, M. Orini, J. D. Tucker, Esther Pueyo and Pablo Laguna.

IEEE Trans on Biomed Eng, 64(7), pp. 1619-1630.

Contribution: First leading author, data analysis, manuscript drafting and editing.

Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers

J. Ramírez, V. Monasterio, A. Mincholé, M. Llamedo, G. Lenis, I Cygankiewicz, A. Bayes de Luna, M. Malik, J. P. Martinez, P Laguna and E. Pueyo

J Electrocardiol 48, pp. 551-557.

Contribution: First leading author, data analysis, manuscript drafting and editing.

QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death

J. Ramírez, P. Laguna, A. Bayés de Luna, M. Malik and E. Pueyo

J Electrocardiol 47, pp. 842-848.

Contribution: First leading author, data analysis, manuscript drafting and editing.

La agrupación no supervisada de electrocardiogramas revela asociaciones con características de resonancia magnética cardíaca

Madrid, J; Sanghvi, M; Young, W J; van Duijvenboden, S; Munroe, P B; Ramírez, J; Mincholé, A

Jornadas de Jóvenes Investigadores del I3A, vol. 13, 2025, ISSN: 2341-4790.

Usón, S; Asensio, C; Ruíz, J J; Candeal, E; Ranera, B; Ramírez, J; Ordovás, L

Jornadas de Jóvenes Investigadores del I3A, vol. 13, 2025, ISSN: 2341-4790.

Predicción a Largo Plazo de Infarto de Miocardio mediante Redes Neuronales Convolucionales Usando Representación Matricial de Electrocardiogramas

Caballero, E; Miguel, A; Munroe, P B; Ramírez, J; Martínez, J P

Proceedings CASEIB 2025, Zaragoza, 2025.

Mejora de la clasificación de latidos cardíacos en señales ECG mediante preentrenamiento autosupervisado a gran escala

Artal, S; Ramírez, J; Miguel, A; Martínez, J P

Proceedings CASEIB 2025, Zaragoza, 2025.

Efecto del sexo y la menopausia sobre patrones electrocardiográficos de repolarización ventricular

Hernández, A; Madrid, J; Gómez, N; Sánchez, C; Munroe, P B; Sanz, A; Mincholé, A; Ramírez, J

Proceedings CASEIB 2025, Zaragoza, 2025.

miR-24-2 modulation in cardiac dysfunction through DNA nanotechnology

Ordovás, L; Hernández-Bellido, N; Postigo, A; Sánchez-Barat, M; Ripalda-Paredes, M; Usón, S; Ruíz-Araca, J J; Candeal, E; Ramírez, J; Ranera, B; Gorospe, M; del Barrio, J; Hernández-Ainsa, S

NanoBio&Med, Barcelona, Spain, 2025.

T-Wave Peak-to-End Morphology Restitution as Biomarker in Brugada Syndrome

Gómez, N; Ramírez, J; Roquero, A I; Palmieri, F; Arbelo, E; Martínez, J P; Laguna, P

Computing in Cardiology 2025, vol. 52, 2025.

Long-Term Prediction of Myocardial Infarction Using Matrix-Based ECG Enabled by Convolutional Neural Networks

Caballero, E; Miguel, A; Munroe, P B; Ramírez, J; Martínez, J P

Computing in Cardiology 2025, vol. 52, 2025.

Sex- and Menopause-Specific ECG Repolarization Patterns

Hernández, A; Madrid, J; Gómez, N; Sánchez, C; Munroe, P B; Sanz, A; Mincholé, A; Ramírez, J

Computing in Cardiology 2025, vol. 52, 2025.

Unsupervised ECG Clustering Reveals Distinct Associations with Cardiac Magnetic Resonance Features

Madrid, J; Sanghvi, M M; Young, W J; van Duijvenboden, S; Munroe, P B; Ramírez, J; Mincholé, A

Computing in Cardiology 2025, vol. 52, 2025.

Combined Estimation of Cross-sectional Area, Flow Rate and Pulse Wave Velocity Using Physics-Informed Neural Networks with D Hemodynamic Model Data

Orera, J; Garcia-Navarro, P; Ramírez, J; Murillo, J

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

A Machine Learning Approach to Detect Hypertension, Diabetes and Cardiovascular Disease from PPG

Searle, G; van Duijvenboden, S; Ramírez, J; Tinker, A; Munroe, P; Lambiase, P; Hughes, A; Orini, M

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

Evaluation of T-wave Time-Warping Dynamics in Patients with Long QT SyndromeA Multilayer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population

Neurys Gómez; Julia Ramírez; Juan Pablo Martínez; Pablo Laguna

2024 13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)

Evaluación de los cambios en la morfología del pico al fin de la onda T, cuantificados mediante “time-warping”, en pacientes con síndrome de Brugada

Gómez, N; Ramírez, J; Roquero, A I; Palmieri, F; Arbelo, E; Martínez, J P; Laguna, P

Proceedings CASEIB 2024, Sevilla, Spain, 2024.

Predicción de Muerte Súbita Cardiaca en pacientes con la enfermedad cardíaca de Chagas a partir de biomarcadores de restitución ventricular derivados del electrocardiograma

Hernández, A; Madeiro, J P; Pedrosa, R C; Laguna, P; Ramírez, J

Proceedings CASEIB 2024, 2024.

ECG Based Unsupervised Clustering Model Predicts Heart Failure and Cardiovascular Diseases in Individuals without Cardiovascular Disease

Madrid, J N; Young, W; van Duijvenboden, S; Munroe, P; Mincholé, A; Ramírez, J

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

Improved Detection of Paroxysmal Atrial Fibrillation Using an ECG-based Semisupervised Model

Artal, S; Martínez, J P; Miguel, A; Ramírez, J

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

Sudden Cardiac Death Prediction in Chagas Heart Disease Patients from ECG-derived Biomarkers of Ventricular Restitution

Hernandez-Mendoza, A; do Vale Madeiro, J P; Pedrosa, R C; Laguna, P; Ramírez, J

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.)

Dynamics of T-peak-to-T-end Morphology Changes in an Open-chest Porcine Model, and Its Relation to Arrhythmic Events

Gómez-Fonseca, N; Ramírez, J; Tsvetkova, A S; Platonov, P; Azarov, J; Martínez, J P; Laguna, P

Proceedings of the LI International Conference on Computing in Cardiology, Karlsruhe, Germany, 2024.

Mejora de la detección de fibrilación auricular paroxística mediante un modelo semisupervisado basado en señales ECG

Artal, S; Martínez, J P; Miguel, A; Ramírez, J

Jornadas de Jóvenes Investigadores del I3A, vol. 12, 2024.

Evaluation of T-wave Time-Warping Dynamics in Patients with Long QT SyndromeA Multilayer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population

Neurys Gómez; Julia Ramírez; Juan Pablo Martínez; Pablo Laguna

2024 13th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)

ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia

J Madrid, P B Munroe, S van Duijvenboden, J Ramírez, A Mincholé

Computing in Cardiology (CinC), Atlanta, GA, USA, 2023, pp. 1-4, doi: 10.22489/CinC.2023.169

A Multilayer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population

J Ramírez, A Miguel, S van Duijvenboden, M Orini, W J Young, A Tinker, P D Lambiase, P B Munroe, J P Martínez

Computing in Cardiology (CinC), Atlanta, GA, USA, 2023, pp. 1-4, doi: 10.22489/CinC.2023.342

Changes in T-Peak-to-T-End Morphology Measured by Time-Warping are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model

N Gómez, J Ramírez, A Martín-Yebra, M M Demidova, P Platonov, JP Martínez, P Laguna

Computing in Cardiology (CinC), Atlanta, GA, USA, 2023, pp. 1-4, doi: 10.22489/CinC.2023.408

Ultra-Short Beat-to-Beat Repolarization Variability Predicts Cardiovascular Events in Individuals Without Cardiovascular Disease

M Orini, S van Duijvenboden, J Ramírez, W J Young, A Tinker, P B Munroe, P D Lambiase

Computing in Cardiology (CinC), Atlanta, GA, USA, 2023, pp. 1-4, doi: 10.22489/CinC.2023.178

Classifying Left Ventricular Hypertrophy from Extracted Morphological Electrocardiogram Biomarkers using Random Forest

Hafiz Naderi, Julia Ramírez, Stefan van Duijvenboden, Esmeralda Ruiz Pujadas, Lin Wang, Karim Lekadir, Steffen E Petersen, Patricia B Munroe

CINC 2022

Combination of Isolation Forest, SMOTE and Ensemble Learning for the classification of Atrial Fibrillation and Ventricular Arrhythmia

Mercedeh J. Rezaei; John R. Woodward; Julia Ramirez; Patricia Munroe

International Conference on Biomedical Innovations and Applications.

Ensemble Learning for the classification of Atrial Fibrillation and Ventricular Arrhythmia

M. J. Rezaei, J. Woodward, J. Ramírez, P.B. Munroe.

International Conference on Biomedical Innovations and Applications.

Weighted Time Warping T-wave Analysis Robust to Delineation Errors: Clinical Implications

F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, E. Pueyo, J.P. Martínez, P. Laguna, J. Ramírez

Computing in Cardiology. Brno (Czech Republic)

«Time-Warping» ponderado sobre la onda T para Reducir el Impacto de Errores de Delineación: Implicaciones Clínicas

F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, E. Pueyo, J.P. Martínez, P. Laguna, J. Ramírez

Congreso Annual de la Sociedad Española de Ingeniería Biomédica.

Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate

S. van Duijvenboden, J. Ramírez, W.J. Young, A. Tinker, P.B. Munroe, P.D. Lambiase, M. Orini

Computing in Cardiology. Rimini (Italy)

Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice?

W.J. Young, J. Ramírez, S. van Duijvenboden, A. Tinker, P.D. Lambiase, P.B. Munroe, M. Orini

Computing in Cardiology. Rimini (Italy)

Potassium Monitoring From Multilead T-wave Morphology Changes During Hemodyalisis: Periodic Versus Principal Component Analysis

F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, A. Martín-Yebra, E. Pueyo, P. Laguna, J.P. Martínez, J. Ramírez

Computing in Cardiology. Rimini (Italy)

Sex Differences in the Morphology of RR-Matched T-waves

J. Ramírez, S. van Duijvenboden, A. Tinker, P.D. Lambiase, P.B. Munroe, M. Orini

Computing in Cardiology. Rimini (Italy)

Interaction Between ECG and Genetic Markers of Coronary Artery Disease

J. Ramírez, S. van Duijvenboden, W.J. Young, A. Tinker, P.D. Lambiase, P.B. Munroe, M. Orini

Computing in Cardiology. Rimini (Italy)

Genetic Architecture of Quantitative Cardiovascular Traits: Blood Pressure, ECG and Imaging Phenotypes

N. Aung, W.J. Young, S. van Duijvenboden, J. Ramírez, S.E. Petersen, P.B. Munroe

Computing in Cardiology. Rimini (Italy)

Data augmentation for heart arrhythmia classification

M. Jafarkhanloo Rezaei, J. Woodward, J. Ramírez, P. B. Munroe

IEEE International Conference on Tools with Artificial Intelligence (ICTAI)

Monitorización en diálisis de la Concentración de Potasio en Sangre mediante los cambios en la morfología multi-lead de la onda T: Comparación Entre usar la transformación en Componentes Periódicas y Principales

Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Dina Ferreira, Alba Martin, Esther Pueyo, Pablo Laguna, Juan Pablo Martínez and Julia Ramírez

XL Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB). Bilbao, Spain

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Serum Potassium Levels

Syed Hassaan Ahmed Bukhari, Flavio Palmieri, Dina Ferreira, Mark Potse, Julia Ramírez, Pablo Laguna, Carlos Sanchez and Esther Pueyo

Computing in Cardiology. Singapore, Singapore

T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients

Flavio Palmieri, Pedro Gomis, José Esteban Ruiz, Beatriz Bergasa, Ferreira Dina, Alba Martin, Syed Hassaan Ahamed, Esther Pueyo, Juan Pablo Martínez, Julia Ramírez and Pablo Laguna

Computing in Cardiology. Singapore, Singapore

Winner of the “ESC-CinC Clinical Needs Translational Award”

Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology

J. Ramírez, S. van Duijvenboden, P. Laguna, E. Pueyo, A. Tinker, P.D. Lambiase, P.B. Munroe, M. Orini.

Computing in Cardiology. Maastrich, The Netherlands.

Winner of the “ESC-CinC Clinical Needs Translational Award”.

T-wave Morphology Restitution in Chronic Heart Failure Patients with Atrial Fibrillation,

F. Palmieri, J.P. Martínez, L. Burattini, J. Ramírez.

Computing in Cardiology. Maastrich, The Netherlands.

Comparison of ECG T-wave Duration and Morphology Restitution Markers for Sudden Cardiac Death Prediction in Chronic Heart Failure

J. Ramirez, M. Orini, E. Pueyo, P. Laguna.

Computing in Cardiology. Rennes, France.

T-wave Morphology Restitution Dependency with Heart Rate Range and Its Association with Sudden Cardiac Death in Chronic Heart Failure

J. Ramirez, M. Orini, E. Pueyo, P. Laguna.

Computing in Cardiology. Rennes, France.

Quantification of T-wave Morphological Variability Using Time-Warping Methods,

J. Ramirez, M. Orini, E. Pueyo, P. Laguna.

European Medical and Biological Engineering and Nordic-Baltic Biomedical Engineering conference. Tampere, Finland.

Cuantificación de la variabilidad de la amplitud de la onda T mediante técnicas de re-parametrización temporal

J. Ramírez, M. Orini, J.D. Tucker, et.al.,

XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB). Valencia, Spain.

An index for T-wave pointwise amplitude variability quantification.

J. Ramírez, M. Orini, J. D. Tucker, Esther Pueyo and Pablo Laguna.

Computing in Cardiology. Vancouver, Canada,

Winner of the “Mortara” mobility fellowship.

Post extrasystolic T wave change to stratify risk of pump failure death in patients with chronic heart failure.

G. Lenis, R. Menges, J. Ramírez, I. Cygankiewicz, A. Bayés de Luna, J.P. Martínez, P. Laguna, O. Dossel,

Computing in Cardiology. Vancouver, Canada, 2016,

Winner of the “Mortara” mobility fellowship.

Modulación circadiana y de género de las relaciones QT/RR y T-pico-a-fin/RR en pacientes con insuficiencia cardiaca

J. Ramírez, P. Laguna y E. Pueyo ,

XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB). Barcelona, Spain.

Circadian pattern and sex differences of QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure patients

J. Ramírez, I. Cygankiewicz, P. Laguna, M. Malik, E. Pueyo,

Computing in Cardiology, Cambridge, MA, United States of America.

Prediction of sudden cardiac death in chronic heart failure patients by analysis of restitution dispersion

J. Ramírez, A. Mincholé, J. Bolea, P. Laguna, E. Pueyo,

Computing in Cardiology. Zaragoza, Spain,

Winner of the Young Investigator Award for the best written and oral presentation.

Caracterización de la respuesta de la repolarización a cambios en el ritmo cardiaco provocados por una prueba de Tilt

J. Ramírez, A. Mincholé, P. laguna, et al,

XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB). San Sebastián, Spain.

Characterization of cardiac repolarization response to heart rate changes provoked by a Tilt test

J. Ramírez, A. Mincholé, P. Laguna, E. Pueyo

Computing in Cardiology. Krakow, Poland,

Winner of the “Bill and Sanders Award” for the best poster presentation.